Hereditary cancer is defined as cancer that has been caused by an inherited genetic variant. Inheriting certain genetic variants does not necessarily mean that cancer will develop, but the lifetime risk is significantly increased, and it is estimated that 5-10% of all cancers are caused by an inherited genetic predisposition.
Genetic testing can identify genetic variants associated with an inherited genetic predisposition to developing certain cancers.
Detection of a gene variantallows individuals to:-
- Make informed lifestyle adjustments.
- Access enhanced screening programs for earlier detection.
- Consider risk-reducing interventions or surgeries, if appropriate.
- Help family members make informed decisions about their own health.
At Visage Medical, all testingservices are fully supported by our experienced GCRB and AHCS registered Genetic Counsellor. Unlike many private providers, we offer pre-and post-test consultations, ensuring you and your family fully understand any increased risks and how to manage them.
Target region for all genes includes full coverage of exons and exon/intron boundaries up to +/- 20bp.
Panel does not cover promoter, 5' or 3' UTR.
CNV calling does not include VHL, HOXB13, POLDI, NF1 and NTHL1 genes.
Interpretation is based on the MANE transcript.
1Reporting is restricted to the truncating or frameshift variants only and c.7271T>G variants in ATM.
2Truncating or frameshift variants in CHEK2.
3Exon deletion of exon 8 to 9 of EPCAM.
4PMS2 and its pseudogene PMS2CL share high sequence homology for exons 12-15. This test does not distinguish whether variants seen in PMS2 originate from PMS2 or PMS2CL. Further testing may be required to disambiguate any variants found in exon 12-15 of PMS2.
- Personalised Pre-Test Consultation - Speak with our consultant Sarah Beck to ensure the test you choose is right for you
- Convenient Sample Collection
- Receive a simple, discreet collection kit delivered to your home
- Easy Return Process - Send your sample back using our prepaid, hassle-free service.
- Reliable Turnaround – Results are processed at a UKAS accredited laboratory and shared promptly
- Expert Post-Test Support – HCPC-registered clinical scientists review your results and provide guidance, recommendations, or onward referrals if needed.
- Peace of Mind for Your Family – Your results may inform testing decisions for relatives
- Future-Proof Reporting – If new research offers additional insights, your report is updated without requiring a new sample
